This "timely, topical, informative [and] exceptionally well written" history explores the impact of disease from prehistoric plagues to Covid-19 (Midwest Book Review).

Historian Paul Chrystal charts how human civilization has grappled with successive pandemics, plagues, and epidemics across millennia. Ranging from prehistory to the present day, this volume begins by defining what constitutes a pandemic or epidemic, taking a close look at 20 historic examples: including cholera, influenza, bubonic plague, leprosy, measles, smallpox, malaria, AIDS, MERS, SARS, Zika, Ebola and, of course, Covid-19. Some less well-known, but equally significant and deadly contagions such as Legionnaires' Disease, psittacosis, polio, the Sweat, and dancing plague, are also covered.

Chrystal provides comprehensive information on each disease, including epidemiology, sources and vectors, morbidity, and mortality, as well as governmental and societal responses, and their political, legal, and scientific consequences. He sheds light on how public health crises have shaped history—particularly in the realms of medical and scientific research and vaccine development. Chrystal also examines myths about infectious diseases, and the role of the media, including social media.