Born into a family with a long psychic lineage, Sylvia Browne became aware as a child that life existed in dimensions beyond our own. Life on the Other Side is Browne's vision of this other existence. The Other Side, she believes, is our home—where we came from and where we will return between lifetimes. Drawing upon both personal and professional experiences, Browne provides a guide for living—one based on her belief that "religion, spirituality and paranormal are consistent parts of God's creation."

Life on the Other Side also explores Browne's theories about reincarnation and a wealth of paranormal experiences, including astral travel, channeling, past life regressions, and near-death encounters.