A virus has infected Arlington, Virginia, home of NERDS headquarters, and it's much worse than your run-of-the-mill flu. Instead of coughing and sneezing, the victims of this voracious virus are transformed into superintelligent criminal masterminds. Soon nearly everyone—including some of the NERDS team—is plotting to take over the world. And who's to blame for this nasty infection? None other than former NERDS teammate Heathcliff Hodges. With more people breaking out into evil cackles every day, it's up to Flinch, the hyperactive superspy with a sweet tooth, to stop the virus. He needs to destroy the virus at its source, and to do that he's going to have to get inside Heathcliff's head—literally. Flinch will have to miniaturize himself and take a fantastic voyage through the supervillain's body to fight white blood cells, stomach acid, and a nest of nasty nanobytes in the hope that he can save the world from . . . the Villain Virus.