David Warburg, newly minted director of the U.S. War Refugee Board, arrives in Rome at war's end, determined to bring aid to the destitute European Jews streaming into the city. Marguerite d'Erasmo, a French-Italian Red Cross worker with a shadowed past, is initially Warburg's guide to a complicated Rome; while a charismatic young American Catholic priest, Monsignor Kevin Deane, seems equally committed to aiding Italian Jews. Soon, Warburg discovers one of history's great scandals - the Vatican ratline, a clandestine escape route maintained by Church officials and providing scores of Nazi war criminals with secret passage to Argentina. Warburg's disillusionment is complete when, turning to American intelligence officials, he learns that the dark secret is not so secret, and that even those he trusts may betray him.