In the lively city of Tijuana, a band of twelve music-loving mice, known as "The Mariachi Mice," find their rhythm in the storeroom of the bustling Marino Café. Feasting on tapas and wine, the six male and six female mice, each with a unique personality and a designated mariachi instrument, dream of sharing their music with the world. They embark on a tour across Mexico, captivating audiences of fellow mice while skillfully evading the clutches of menacing cats. Their talent doesn't go unnoticed, and a human record producer catapults them to stardom. Overnight, they are living a life of luxury, complete with fancy sports cars and designer mouseholes. However, their newfound fame causes them to forget their humble beginnings and their families. A chance encounter with a poor mouse family serves as a poignant reminder of their roots, prompting them to return to their hometown. They use their wealth to enrich their community, building schools and hospitals. The Mariachi Mice continue to make music, their songs now imbued with a deeper sense of purpose, gratitude, and the enduring importance of family and community.