Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing.
Topics included in the book include:
- the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix.
- fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation
- the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential.
- strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration.
- the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use
Part 1 covers techniques for tissue engineering, wound healing and skin engineering. It also presents reviews on techniques such as acellular synthesis and 3D bioprinting. Materials highlighted in this part include chitosan-based nanoparticles, nanocollagen-based materials and plant based composites.
Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.