Ohio River

West of Fort Henry, in the wild and lawless country, the tribes are massing for an attack that will destroy the isolated white settlements. Settlers are doomed unless a few grizzled veterans of the Indian Wars can turn back the angry natives. One veteran is a man of legend and mystery: Wetzel rides through a borderland crawling with outlaws and savages, vowing to rid the frontier of its ruthless predators and to make the territory safe for the bold pioneers of the American West.