When a terrorist organization take control of an island research facility, Rob Cashen and his band of mercenaries are recruited to eliminate the terrorists and rescue the hostages. Upon arrival, they realize something has gone horribly wrong. Terrorist outposts are in ruins, guns and equipment are left abandoned, but no bodies can be found. In the ensuing investigation, Rob discovers the horrific consequences of genetic tampering.

Hordes of giant scorpions have taken over the island. Their hunger is insatiable, their numbers are increasing, and their food supply is dwindling. Armed with razor-sharp claws and javelin-like stingers, they mercilessly slaughter anything in their path. Now the team must fight for survival as the horde of scorpions pursue them through the jungle.