All Riley needs is one experimental test subject to try out his new gender-transformation beam. But when he surprises his friend Liam with an unexpected male to female gender swap, something goes horribly wrong: Liam's new body becomes hormonally supercharged with an insatiable sexual appetite.

Liam vows revenge, but accidentally mixes things up when he tries to transform Riley's body - giving him most of the body of a hot new girl, with one long, hard exception! Now the girls are locked in a battle for revenge, while trying to satiate their need to fill as many holes as possible with as many men as they can find!